Category: alkaloid
Aliases: Yohimbe, Pausinystalia johimbe, Corynanthe johimbe, yohimbe extract, yohimbe bark extract
Dried bark of Pausinystalia johimbe, a West African tree used as a stimulant / aphrodisiac and fat-loss supplement. Its activity is dominated by yohimbine — the major alkaloid, an α₂-adrenoceptor antagonist — accompanied by a family of minor yohimbane / corynanthe indole alkaloids (rauwolscine, corynanthine, β-yohimbine, ajmalicine and others) and a significant astringent condensed-tannin fraction. Whole-bark exposure is a mixture: the modeled effect tracks the yohimbine component, while the minor alkaloids add α-adrenergic / serotonergic activity. Narrow safety window; content varies widely between products.
Parent botanical/extract entry (pk_unauthored: mixture). Constituent slugs authored in the 2026-06-27 yohimbe-bark wave plus the pre-existing yohimbine. mg_per_g values are a representative composite of typical ranges (label/literature/supplied profile), not a single assay; major-alkaloid presence per PMID:26391406, minor alkaloids per PMID:23657953 / PMID:30059216.