Corynantheine

Category: alkaloid

Aliases: (+)-Corynantheine

Pharmacological Mechanism

A corynanthe-type indole alkaloid of yohimbe bark (Pausinystalia johimbe) — the structural class named for the genus Corynanthe (yohimbe’s historical genus). It has a seco (ring-opened) corynanthe skeleton with a vinyl group and a methoxy-acrylate side chain, distinguishing it from the pentacyclic yohimbine. Its pharmacology is not well characterised.

Target Organ Systems

• nervous

Notes

PubChem CID 3037997 (C22H26N2O3, MW 366.5). Reported among the corynanthe-type indole alkaloids characterised in yohimbe-bark profiling (PMID:23657953).

Chemical Identifiers

• PubChem CID: 3037997
• Formula: C22H26N2O3
• Molecular weight: 366.5 g/mol
• InChIKey: TZUGIFAYWNNSAO-XPOGPMDLSA-N
• SMILES: CO/C=C(\[C@H]1C[C@H]2C3=C(CCN2C[C@@H]1C=C)C4=CC=CC=C4N3)/C(=O)OC

References

• PMID 23657953