Pharmacology Registry

Bioassays & Screening 12 assays Radioligand binding, patch clamp, calcium imaging, FRET, BRET, ELISA, Western blot, HTS, and Ames test Experimental & Genetic Models 12 models Knockout mice, Cre-Lox, Tet-On/Off, optogenetics, DREADDs, pooled CRISPR screens, iPSCs, and organoids Research Tool Compounds 12 tool compounds Tetrodotoxin, forskolin, IBMX, bicuculline, CNQX, dizocilpine, ouabain, wortmannin, U0126, and thapsigargin

Computational & Modeling Software 12 software AutoDock, PyMOL, ChimeraX, AlphaFold, RDKit, Open Babel, GROMACS, AMBER, NONMEM, and CellProfiler Chemical & Target Databases 12 databases ChEMBL, PubChem, IUPHAR GtoPdb, DrugBank, BindingDB, PDB, UniProt, PharmGKB, ZINC, and KEGG Pharmacokinetic & PD Parameters 12 parameters IC50, EC50, Kd, Hill coefficient, therapeutic index, LD50, half-life, Vd, clearance, and Lipinski's RO5