Pseudoyohimbine

Category: alkaloid

Aliases: ψ-Yohimbine, psi-Yohimbine

Pharmacological Mechanism

A minor indole alkaloid of yohimbe bark (Pausinystalia johimbe) and a stereoisomer of yohimbine (a 3-epi configuration of the pentacyclic yohimban ring system). Its own pharmacology is not characterised; affinity for adrenergic or serotonergic receptors has not been quantified for this isomer.

Target Organ Systems

• nervous

Notes

PubChem CID 251562 (C21H26N2O3, MW 354.4). Present in yohimbe bark: PMID:23657953 (UPLC-IM-QTOF indole-alkaloid profile of yohimbe bark).

Chemical Identifiers

• PubChem CID: 251562
• Formula: C21H26N2O3
• Molecular weight: 354.4 g/mol
• InChIKey: BLGXFZZNTVWLAY-AECJZGCLSA-N
• SMILES: COC(=O)[C@H]1[C@H](CC[C@@H]2[C@@H]1C[C@@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)O

References

• PMID 23657953