Yohimbinic acid

Category: alkaloid

Aliases: Yohimbic acid

Pharmacological Mechanism

A minor indole alkaloid of yohimbe bark (Pausinystalia johimbe) — the free-carboxylic-acid analog of yohimbine (yohimbine is its methyl ester). Its own pharmacology is not characterised and no validated receptor-affinity data for the isolated compound were found.

Target Organ Systems

• nervous

Notes

PubChem CID 72131 (C20H24N2O3, MW 340.4; PubChem Title "Yohimbic Acid"). Present in yohimbe bark/extracts: PMID:25905738 lists "yohimbic acid" among yohimbine analogs detected by LC/QTOF-MS.

Chemical Identifiers

• PubChem CID: 72131
• Formula: C20H24N2O3
• Molecular weight: 340.4 g/mol
• InChIKey: AADVZSXPNRLYLV-GKMXPDSGSA-N
• SMILES: C1C[C@@H]([C@@H]([C@@H]2[C@@H]1CN3CCC4=C([C@@H]3C2)NC5=CC=CC=C45)C(=O)O)O

References

• PMID 25905738