Iron

Category: mineral

Aliases: Fe, Ferrous bisglycinate, Ferrous sulfate, Heme iron

Pharmacological Mechanism

Fe cycles between ferrous (Fe²⁺) and ferric (Fe³⁺) states, enabling electron transfer in hemoproteins (hemoglobin, myoglobin, cytochromes a/b/c) and iron-sulfur clusters (ETC Complex I/II, aconitase). Absorbed as Fe²⁺ via DMT1 in duodenum; stored as ferritin; transported as transferrin-bound Fe³⁺. Systemic absorption gated by hepcidin (iron-status-responsive).

Dosing Guidelines

Target Organ Systems

Interactions