Category: metabolite
Aliases: Trimethylglycine, Betaine, Betaine anhydrous
Methyl donor to homocysteine via betaine-homocysteine methyltransferase (BHMT) — a B12-independent remethylation route parallel to methionine synthase. Complementary methyl donor for high-methylation-demand protocols (e.g., NMN → NAD⁺ → methylated nicotinamide). Also a renal osmolyte and a performance-enhancement ergogenic at ~2.5 g/d (mechanism uncertain — possibly via methyl support for creatine synthesis).
PO: 2h