Phenylalanine

Category: amino-acid

Aliases: Phe, F, L-Phenylalanine

Pharmacological Mechanism

Hydroxylated by phenylalanine hydroxylase (PAH, [[bh4_cycle]]-dependent) to tyrosine — the [[catecholamine_synthesis]] precursor. PAH deficiency causes phenylketonuria (PKU). Precursor to adrenaline, [[norepinephrine]], [[dopamine]]; also to melanin via tyrosinase.

Dosing Guidelines

Target Organ Systems