Category: neurotransmitter
Aliases: Noradrenaline, NE, NA
[[catecholamine_synthesis]] synthesised from [[dopamine]] by dopamine-β-hydroxylase (DβH, Cu + ascorbate dependent). Dominant [[adrenergic_receptor_signaling]] α₁ vasoconstrictor; also β₁ inotropic, weaker β₂. Sympathetic postganglionic neurotransmitter and locus coeruleus CNS projection neurotransmitter (arousal, attention, noradrenergic tone).