Valine

Category: amino-acid

Aliases: Val, V, L-Valine, BCAA

Pharmacological Mechanism

One of three BCAAs. Glucogenic (catabolised to succinyl-CoA). Catabolised extrahepatically by BCKDH — same enzyme complex as Leu/Ile. Deficiency in MSUD (maple syrup urine disease).

Half-Life (t½)

PO: 1h

Dosing Guidelines

• PO: Typical 2.67g (Range: 2 - 4 g)

Target Organ Systems

• musculoskeletal

Interactions

• Leucine