One of three BCAAs. Glucogenic (catabolised to succinyl-CoA). Catabolised extrahepatically by BCKDH — same enzyme complex as Leu/Ile. Deficiency in MSUD (maple syrup urine disease).
Half-Life (t½)
PO: 1h
Dosing Guidelines
PO: Typical 2.67 g (Range: 2–4 g)
Target Organ Systems
musculoskeletal
Interactions
Leucine (synergistic): BCAA pool; 2:1:1 L:I:V blend is standard.