Category: lipid
Aliases: DGLA, 20:3 n-6, Dihomo-gamma-linolenic acid
20:3 n-6 polyunsaturated fatty acid; the elongation product of γ-linolenic acid (GLA) and direct precursor of the anti-inflammatory series-1 prostaglandins (PGE1) and 15-HETrE. Sits one Δ5-desaturation step upstream of arachidonic acid, so DGLA accumulation biases eicosanoid output toward anti-inflammatory mediators.