Kupffer Cell

Specialized macrophages located in the sinusoids of the liver, acting as resident immune cells that phagocytose pathogens, cellular debris, and old red blood cells.

Key Functions:

• Phagocytoses bacteria, toxins, and cellular debris from portal blood.
• Removes old or damaged erythrocytes.
• Acts as a key immune surveillance cell in the liver.

Interacting Systems & Components:

• Macrophage (type of)
• Liver (located in)
• Immune System (component of)
• Erythrocyte (removes old)
• Digestive System (part of)