Lipopolysaccharides

Serves as a major component of the outer membrane of Gram-negative bacteria, acting as a potent endotoxin that triggers strong immune responses in hosts.

Key Functions:

• Contributes to the structural integrity of bacterial outer membranes.
• Activates innate immune cells, leading to inflammation.
• Responsible for many of the symptoms of bacterial sepsis.

Interacting Systems & Components:

• Gram-negative Bacteria (component of)
• Immune System (activates innate immunity)
• Toll-like Receptors (specifically TLR4, receptor for LPS)
• Cytokines (induces production of)