Platelet-Activating Factor

Acts as a potent phospholipid activator and mediator of many leukocyte functions, platelet aggregation, and inflammatory responses.

Key Functions:

• Induces platelet aggregation and degranulation.
• Potent mediator of inflammation and allergic reactions.
• Increases vascular permeability and smooth muscle contraction.

Interacting Systems & Components:

• Platelets (activates)
• Leukocytes (mediates functions)
• Inflammatory Response (key mediator)
• Platelet-Activating Factor Receptor (binds to)
• Lysophosphatidylcholine (synthesized from)