SMAD4

Transcription factor in TGF-β signaling pathway.

Key Functions:

• Regulates cell growth and differentiation.
• Suppresses tumor formation.

Interacting Systems & Components:

• Immune System (cancer prevention)
• TGF-β (upstream signaling)
• Nucleus (transcription site)

Gene Record

Approved symbol: SMAD4

Approved name: SMAD family member 4

Locus: 18q21.2

Locus type: gene with protein product

HGNC: HGNC:6770

From the HGNC naming authority.