Zinc Picolinate

Category: mineral

Aliases: zinc

Pharmacological Mechanism

Cofactor for >300 enzymes; immune and androgen support.

Half-Life (t½)

PO: 50h

Dosing Guidelines

• PO: Typical 15 (Range: 8–40)

Target Organ Systems

• immune-hematologic

Interactions

• Zinc (synergistic): Same elemental mineral — picolinate is a commonly chosen well-tolerated form.
• Copper (caution): Chronic Zn >25 mg/d depletes Cu regardless of form.

Notes

Avoid >40mg/day chronic; can cause copper deficiency. Picolinate form ~30% bioavailable.

Pathways It Modulates

• Mineral enzyme cofactor overview (cofactor) — Zn delivery (picolinate chelate)

Chemical Identifiers

• PubChem CID: 9904746
• Formula: C12H8N2O4Zn
• Molecular weight: 309.62 g/mol
• InChIKey: NHVUUBRKFZWXRN-UHFFFAOYSA-L
• SMILES: C1=CC=NC(=C1)C(=O)[O-].C1=CC=NC(=C1)C(=O)[O-].[Zn+2]

References

• PMID 3630857