Magnesium L-Threonate

Category: mineral

Aliases: magtein, Magtein, Mg L-threonate, MgT, magnesium-threonate

Pharmacological Mechanism

Mg²⁺ chelated with two L-threonate (vitamin C metabolite) molecules. The threonate moiety is proposed to facilitate CNS uptake — Slutsky 2010 showed oral MgT raised rat CSF Mg²⁺ by ~15% where other Mg forms did not, with associated upregulation of NR2B-containing NMDA receptors and improved hippocampal LTP / learning. Elemental Mg content is only ~8% by weight, so MgT is not the right form for systemic Mg repletion; it's specifically a cognition-targeted form.

Dosing Guidelines

Target Organ Systems

Interactions