Beta-Carotene

Category: vitamin

Aliases: β-Carotene, Provitamin A

Pharmacological Mechanism

Provitamin A: cleaved by BCMO1 in intestinal enterocytes into two retinal molecules, which are reduced to retinol. Conversion is regulated by vitamin A status — unlike preformed retinol, excess β-carotene does not accumulate as toxic retinoids. Also functions as a lipid-phase antioxidant and singlet-oxygen quencher.

Half-Life (t½)

PO: 888h

Dosing Guidelines

Target Organ Systems