Raphe Nuclei

A cluster of nuclei located along the midline of the brainstem, serving as the primary source of serotonin in the brain, influencing mood, sleep, pain, and arousal.

Key Functions:

• Produce and release serotonin.
• Regulate sleep-wake cycles and circadian rhythms.
• Modulate mood, anxiety, and depression.
• Involved in pain perception and regulation.

Interacting Systems & Components:

• Brainstem (located within)
• Serotonin (primary neurotransmitter produced)
• Reticular Formation (part of)
• Forebrain (projects widely to)
• Mood Regulation (key for)