PI3K

Phosphoinositide 3-kinase, regulates cell growth and survival.

Key Functions:

• Activates AKT/mTOR signaling pathway.
• Promotes cell proliferation and metabolism.

Interacting Systems & Components:

• AKT1 (downstream target)
• Immune System (cancer regulation)
• Insulin Receptor (upstream signaling)

Gene Record

Approved symbol: PIK3CA

Approved name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

Locus: 3q26.32

Locus type: gene with protein product

HGNC: HGNC:8975

From the HGNC naming authority.