PTEN

Tumor suppressor regulating cell growth.

Key Functions:

• Inhibits PI3K/AKT signaling pathway.
• Prevents tumor formation.

Interacting Systems & Components:

• Immune System (cancer prevention)
• AKT (regulated pathway)
• Nucleus (expression site)

Gene Record

Approved symbol: PTEN

Approved name: phosphatase and tensin homolog

Locus: 10q23.31

Locus type: gene with protein product

HGNC: HGNC:9588

From the HGNC naming authority.