HFE

Regulates iron homeostasis; mutations cause hemochromatosis.

Key Functions:

• Controls iron absorption in intestines.
• Prevents iron overload.

Interacting Systems & Components:

• Digestive System (iron absorption)
• Transferrin (interacting protein)
• Liver (expression site)

Gene Record

Approved symbol: HFE

Approved name: homeostatic iron regulator

Locus: 6p22.2

Locus type: gene with protein product

HGNC: HGNC:4886

From the HGNC naming authority.