Thymosin β4

Category: peptide

Aliases: Tβ4, TBP-4 (full-length)

Pharmacological Mechanism

Ubiquitous G-actin-sequestering protein — 5–15% of total intracellular protein in many cell types. Controls actin polymerisation / depolymerisation dynamics critical to cell migration. Promotes angiogenesis via upregulation of VEGF-A + FGF-2. Phase 2 trials for corneal / skin / cardiac repair have been positive; full-length molecule is longer-acting than TB-500 fragment.

Dosing Guidelines

Target Organ Systems

Interactions