Pantethine

Category: vitamin

Aliases: Bis-pantethine disulfide, Activated B5

Pharmacological Mechanism

Dimeric disulfide form of pantetheine, the immediate CoA precursor (one step from CoA vs. three from pantothenic acid). Proposed dyslipidemia mechanism is inhibition of HMG-CoA reductase and acyl-CoA:cholesterol acyltransferase (ACAT) at the pantetheine stage.

Half-Life (t½)

PO: 0.067h

Dosing Guidelines

Target Organ Systems

Interactions