Sermorelin (GHRH 1-29) with 4 amino-acid substitutions (D-Ala² / Gln⁸ / Ala¹⁵ / Leu²⁷) that resist DPP-IV degradation — extends plasma t½ ~4× vs native sermorelin (~30 min vs ~11 min). Distinct from DAC-variant CJC-1295 which has much longer t½.
Dosing Guidelines
SC: Typical 133 mcg (Range: 100–200 mcg)
Target Organ Systems
endocrine
musculoskeletal
Interactions
CJC-1295 (DAC) (synergistic): Same base sequence; DAC variant has 7-day t½ vs. 30-min for no-DAC. Pick one based on pulsatile vs sustained strategy.