Lion's Mane

Category: nootropic

Aliases: hericium erinaceus

Pharmacological Mechanism

Hericenones and erinacines stimulate NGF synthesis.

Half-Life (t½)

PO: 6h

Dosing Guidelines

• PO: Typical 1000 (Range: 500–3000)

Target Organ Systems

• nervous

Pathways It Modulates

• BDNF / TrkB neurotrophic signaling (activator) — NGF + BDNF (hericenones / erinacines)
• Medicinal mushroom β-glucans (activator) — NGF synthesis stimulation (hericenones + erinacines)

References

• PMID 18844328