Category: peptide
Aliases: Metastin, KISS1 gene product
Upstream master regulator of GnRH release — activates KISS1R (GPR54) on hypothalamic GnRH neurons. Critical for reproductive-axis initiation (puberty) and maintenance. Proposed clinical uses include hypogonadotropic hypogonadism, IVF ovulation trigger (bypasses some HCG safety concerns), and PCOS research.
IV: 0.46h