Nociceptors

Category
Pain
Function
Mechanical, thermal, chemical, polymodal pain
Quantity
Millions of free endings (Aδ + C)
Density
High throughout skin; also muscle, joint, viscera
Distribution
Skin, deep somatic tissues, most viscera

Relative Deployment

Notes

Fast Aδ “first pain” and slow C “second pain.” Spatial acuity is coarser than touch but still follows a similar body gradient (finest on fingertips and face).

Interacting Systems & Components