Category: biosynthesis
Nucleosides + nucleotides as dietary supplements rather than de novo synthesis substrates. CDP-choline (citicoline) — provides cytidine + choline; stroke recovery + cognitive enhancement; raises both phosphatidylcholine + acetylcholine biosynthesis. Uridine — converted to UMP/UDP/UTP; precursor for membrane phosphatidylcholine via Kennedy pathway; bipolar + sleep claims. NAD-precursor stack: NMN (nicotinamide mononucleotide), NR (nicotinamide riboside), NAAD, NaMN — bypass the rate-limiting NAMPT step; longevity + mitochondrial health claims; oral PK + tissue NAD+ elevation under active research. Inosine — degraded to uric acid; gout precursor + claimed performance enhancer (debated). Adenosine + adenosine-cousins (cordycepin = 3'-deoxyadenosine — covered in mushroom pathway).