SOX2

Transcription factor maintaining pluripotency.

Key Functions:

• Regulates stem cell self-renewal.
• Supports neural and eye development.

Interacting Systems & Components:

• Nervous System (neural development)
• OCT4 (co-regulator)
• Stem Cell (expression site)

Gene Record

Approved symbol: SOX2

Approved name: SRY-box transcription factor 2

Locus: 3q26.33

Locus type: gene with protein product

HGNC: HGNC:11195

From the HGNC naming authority.