SIRT1

Sirtuin 1, regulates cellular aging and metabolism.

Key Functions:

• Deacetylates histones and proteins.
• Modulates longevity and stress response.

Interacting Systems & Components:

• Metabolic System (metabolic regulation)
• TP53 (target protein)
• Nucleus (expression site)

Gene Record

Approved symbol: SIRT1

Approved name: sirtuin 1

Locus: 10q21.3

Locus type: gene with protein product

HGNC: HGNC:14929

From the HGNC naming authority.