JAK2

Tyrosine kinase involved in cytokine signaling.

Key Functions:

• Activates STAT signaling pathways.
• Regulates immune and hematopoietic functions.

Interacting Systems & Components:

• Immune System (immune signaling)
• STAT (downstream target)
• Cytokine Receptor (upstream signaling)

Gene Record

Approved symbol: JAK2

Approved name: Janus kinase 2

Locus: 9p24.1

Locus type: gene with protein product

HGNC: HGNC:6192

From the HGNC naming authority.