BRCA1

Tumor suppressor involved in DNA repair.

Key Functions:

• Repairs double-strand DNA breaks.
• Prevents breast and ovarian cancer.

Interacting Systems & Components:

• Immune System (cancer prevention)
• BRCA2 (related gene)
• Nucleus (expression site)

Gene Record

Approved symbol: BRCA1

Approved name: BRCA1 DNA repair associated

Locus: 17q21.31

Locus type: gene with protein product

HGNC: HGNC:1100

From the HGNC naming authority.