ABL1

Tyrosine kinase, regulates cell growth; linked to leukemia.

Key Functions:

• Controls cell proliferation and apoptosis.
• Forms BCR-ABL fusion in CML.

Interacting Systems & Components:

• Immune System (cancer regulation)
• BCR (fusion partner)
• Nucleus (expression site)

Gene Record

Approved symbol: ABL1

Approved name: ABL proto-oncogene 1, non-receptor tyrosine kinase

Locus: 9q34.12

Locus type: gene with protein product

HGNC: HGNC:76

From the HGNC naming authority.