Zeaxanthin

Category: vitamin

Pharmacological Mechanism

Xanthophyll carotenoid concentrated alongside lutein in retinal macula. AREDS2 macular protection. Stereoisomer meso-zeaxanthin is dietarily rare but accumulates in foveal center.

Half-Life (t½)

PO: 24h

Dosing Guidelines

• PO: Typical 2 mg (Range: 1–4 mg)

Target Organ Systems

• endocrine

Pathways It Modulates

• Vitamin antioxidant axis (activator) — macular pigment

Chemical Identifiers

• PubChem CID: 5280899
• Formula: C40H56O2
• Molecular weight: 568.87 g/mol
• InChIKey: JKQXZKUSFCKOGQ-QAYBQHTQSA-N
• SMILES: CC1=C(C(C[C@@H](C1)O)(C)C)/C=C/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C=C/C2=C(C[C@H](CC2(C)C)O)C)\C)\C)/C)/C

References

• PMID 15137922