Valsartan

Category: pharmacological

Aliases: Diovan

Pharmacological Mechanism

AT1 receptor blocker — no active metabolite (unlike losartan). Largely unchanged renal clearance; minimal CYP metabolism → fewer DDIs. Component of sacubitril/valsartan (Entresto) for HFrEF.

Half-Life (t½)

PO: 7h

Dosing Guidelines

• PO: Typical 160mg (Range: 40 - 320 mg)

Target Organ Systems

• renal