Valerenic acid

Category: terpenoid

Pharmacological Mechanism

Sesquiterpenoid; positive allosteric modulator at GABA-A β3 subunit. Primary anxiolytic + sleep-promoting bioactive in Valeriana officinalis root extracts. Standardized supplements often target ≥0.8% valerenic acid as a marker.

Half-Life (t½)

PO: 1.1h

Dosing Guidelines

• PO: Typical 6mg (Range: 1 - 20 mg)

Target Organ Systems

• nervous