Umeclidinium

Category: pharmacological

Aliases: Incruse Ellipta

Pharmacological Mechanism

Inhaled LAMA — once-daily M3-preferring muscarinic antagonist for COPD. Component of triple-therapy inhalers (Trelegy = umeclidinium + vilanterol + fluticasone furoate). Quaternary structure limits systemic absorption.

Half-Life (t½)

INH: 11h

Dosing Guidelines

• INH: Typical 0.0625mg (Range: 0.0625 - 0.0625 mg)

Target Organ Systems

• nervous
• respiratory