Tranylcypromine

Category: pharmacological

Aliases: Parnate

Pharmacological Mechanism

Irreversible non-selective MAOI with weaker dietary-tyramine restrictions than phenelzine but still mandatory. Faster onset (~10 days vs 4 weeks) than phenelzine. Refractory depression.

Half-Life (t½)

PO: 2.5h

Dosing Guidelines

• PO: Typical 30mg (Range: 10 - 60 mg)

Target Organ Systems

• nervous