Thiopental

Category: pharmacological

Aliases: Pentothal, Sodium thiopental

Pharmacological Mechanism

Ultra-short-acting barbiturate — GABA-A positive allosteric modulator. Once the workhorse induction anesthetic; supplanted by propofol. Still used for refractory status epilepticus + execution-protocol contexts. Significant cardiovascular depression at induction doses.

Half-Life (t½)

IV: 11h

Dosing Guidelines

Target Organ Systems