Tetrahydrocannabivarin

Category: alkaloid

Aliases: tetrahydrocannabivarin, THCV, delta-9-THCV

Pharmacological Mechanism

Propyl-side-chain analog of THC. Behaves as a CB1 antagonist / low-efficacy ligand at low doses and a CB1 partial agonist at higher doses; CB2 partial agonist. Studied for appetite suppression and metabolic effects, in contrast to THC's orexigenic action.

Dosing Guidelines

• INH: Typical 5mg (Range: 1 - 10 )
• PO: Typical 10mg (Range: 5 - 20 )

Target Organ Systems

• nervous
• digestive