Testosterone propionate

Category: hormone

Aliases: Test Prop

Pharmacological Mechanism

Short-chain ester prodrug of testosterone; after IM depot release it is hydrolyzed to free testosterone, the natural AR agonist, which also 5α-reduces to DHT and aromatizes to estradiol. Full androgenic + anabolic spectrum. The short ester gives a rapid rise and short duration vs the longer cypionate/enanthate esters, so it is injected more frequently.

Dosing Guidelines

• IM: Typical 100 (Range: 25–200)

Target Organ Systems

• endocrine
• reproductive
• musculoskeletal
• cardiovascular

Notes

PubChem CID 5995 (propionate ester). AR affinity belongs to the released free testosterone (see testosterone / testosterone-cypionate). No testosterone-propionate half-life is abstract-verbatim — the "~19 h" figure traces only to the Behre/Nieschlag review (see AUTHORING_GAPS).

Chemical Identifiers

• PubChem CID: 5995
• Formula: C22H32O3
• Molecular weight: 344.5 g/mol
• InChIKey: PDMMFKSKQVNJMI-BLQWBTBKSA-N
• SMILES: CCC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C