Tadalafil

Category: pharmacological

Aliases: Cialis, Adcirca

Pharmacological Mechanism

PDE5 inhibitor with ~17h half-life — supports both on-demand and daily dosing. CYP3A4 substrate. Approved for erectile dysfunction, BPH, and pulmonary arterial hypertension.

Half-Life (t½)

PO: 17.5h

Dosing Guidelines

• PO: Typical 10mg (Range: 2.5 - 20 mg)

Target Organ Systems

• cardiovascular
• respiratory
• digestive
• reproductive