Category: polyphenol
Aliases: 1-Isothiocyanato-4-(methylsulfinyl)butane, SFN
Released from glucoraphanin by the enzyme myrosinase (from plant or gut microbiota) upon chewing/processing — sulforaphane is the active isothiocyanate. Potent Nrf2 activator: alkylates KEAP1 cysteines → disinhibits Nrf2 → transcription of phase II detoxification / antioxidant genes (glutathione synthesis, NQO1, HO-1). Also HDAC inhibitor at high concentrations.
PO: 1.77h