Category: pharmacological
Aliases: Component of Bactrim / Septra
Sulfonamide antibiotic — competitive inhibitor of bacterial dihydropteroate synthase (DHPS) blocking folate synthesis. Always co-formulated with trimethoprim for synergistic folate-pathway blockade. CYP2C9 inhibitor (raises warfarin INR).
PO: 10h, IV: 10h