Sufentanil

Category: pharmacological

Aliases: Sufenta

Pharmacological Mechanism

Synthetic μ-opioid agonist — phenylpiperidine class with ~10× fentanyl potency. Used in anesthesia + obstetric epidural / spinal analgesia. CYP3A4 substrate.

Half-Life (t½)

IV: 2.73h

Dosing Guidelines

• IV: Typical 1 mcg (Range: 0.1–30 mcg)

Target Organ Systems

• nervous
• digestive

Pathways It Modulates

• Opioid receptor signaling (activator) — μ-opioid receptor

Chemical Identifiers

• PubChem CID: 41693
• Formula: C22H30N2O2S
• Molecular weight: 386.55 g/mol
• InChIKey: GGCSSNBKKAUURC-UHFFFAOYSA-N
• SMILES: CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC3=CC=CS3)COC

References

• PMID 6238552