Category: flavonoid
Principal flavonolignan in the silymarin complex from Silybum marianum. Hepatoprotective via free-radical scavenging, hepatocyte membrane stabilization, inhibition of CYP3A4/P-gp (clinical DDI risk), and Amanita phalloides poisoning antidote (IV silibinin = Legalon SIL). Mixed silybin A + B diastereomers in extracts.
PO: 6h, IV: 6h