Sertraline

Category: pharmacological

Aliases: Zoloft

Pharmacological Mechanism

SSRI with modest dopamine-transporter activity at high doses (σ-1 binding contributes). Weaker CYP interactions than fluoxetine. 26-h t½.

Half-Life (t½)

PO: 26h

Dosing Guidelines

• PO: Typical 100mg (Range: 50 - 200 mg)

Target Organ Systems

• nervous