Rizatriptan

Category: pharmacological

Aliases: Maxalt

Pharmacological Mechanism

5-HT1B/1D agonist — second-generation triptan; faster oral onset and higher receptor potency than sumatriptan. Orally disintegrating tablet useful when migraine causes nausea. MAO-A substrate (dose adjust with propranolol).

Half-Life (t½)

PO: 2h

Dosing Guidelines

• PO: Typical 10mg (Range: 5 - 10 mg)

Target Organ Systems

• nervous