Risedronate

Category: pharmacological

Aliases: Actonel

Pharmacological Mechanism

Aminobisphosphonate — same osteoclast apoptosis mechanism as alendronate. Less GI irritation; weekly + monthly dosing options. Postmenopausal osteoporosis + glucocorticoid-induced osteoporosis prevention.

Half-Life (t½)

PO: 480h

Dosing Guidelines

• PO: Typical 35mg (Range: 5 - 150 mg)

Target Organ Systems

• digestive
• musculoskeletal